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All about Cicatricial pemphigoid and its relation with LDN

Cicatricial Pemphigoid is a type of pemphigoid which is an autoimmune disorder that affects the skin. Cicatricial pemphigoid is also known as mucous membrane pemphigoid. In this type of pemphigoid, blisters form on the mucous membranes in the skin. Rashes and blisters form on areas affected with pemphigoid and these may spread in other areas if left untreated.

Cicatricial pemphigoid most commonly occurs in the mouth and eyes, other parts likely to get affected are the nose, throat, genitals, anus, etc. in more severe cases, it may affect the face, scalp, or neck. If a pemphigoid develops in the eyes, it is called Ocular Cicatricial Pemphigoid (OCP). Cicatricial Pemphigoid most commonly develops in people whose ages are between 40 and 70 years. Women have twice a greater risk of developing Cicatricial Pemphigoid than men. Also, it usually develops in people who have a weaker immune system.


When to see a doctor


Cicatricial Pemphigoid requires immediate medical attention as it can create severe complications if left untreated for a long time. The blisters in the mouth can make eating difficult. If it gets severe, you may not be able to eat at all which can result in malnutrition or weight loss. Ocular Cicatricial Pemphigoid (OCP) can cause scarring and redness in the eyes. It may lead to vision impairment or complete blindness if any kind of compromise is made in eyes or respiratory conditions. The blisters usually become dangerous ulcers that may even result in loss of skin and scarring. Scarring can ultimately cause disfigurement.


How can you treat cicatricial pemphigoid?


The treatment of cicatricial pemphigoid depends on where it is formed and how severe the symptoms of cicatricial pemphigoid are. The doctors usually recommend the following medications and home remedies for treating cicatricial pemphigoid:

● Steroid based medications

● Steroid based ointments

● Painkillers

● Using lubricants, moisturizers on the wounds

● Eating a soft diet so that blisters can be prevented from worsening

● Taking care of dental hygiene

● In case the lesions become severe, the doctors may recommend surgery


Low Dose Naltrexone (LDN) and cicatricial pemphigoid


In recent years, research has shown that the drug “Naltrexone” has done wonders. If given in low dosage, it can help to treat cancers, autoimmune disorders, etc. Low Dose Naltrexone (LDN) can treat cicatricial pemphigoid with least or no side effects at all. You can visit the harbor compounding pharmacy for more details.

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